Pharmacokinetic interaction studies of tanshinones with tolbutamide, a model CYP2C11 probe substrate, using liver microsomes, primary hepatocytes and in vivo in the rat.

Pharmacokinetic interaction studies of tanshinones with tolbutamide, a model CYP2C11 probe substrate, using liver microsomes, primary hepatocytes and in vivo in the rat. post thumbnail image

The results of Danshen and its lively parts (tanshinone I, tanshinone IIA, dihydrotanshinone and cryptotanshinone) on tolbutamide 4-hydroxylation was investigated within the rat. Danshen (0.125-2mg/ml) decreased 4-hydroxy-tolbutamide formation in vitro and in vivo. Enzyme kinetics research confirmed that inhibition of tolbutamide 4-hydroxylase exercise was aggressive and concentration-dependent. The Ok(i) values of the tanshinones have been: dihydrotanshinone (8.92microM), cryptotanshinone (24.5microM), tanshinone I (80.3microM) and tanshinone IIA (242.9microM). In freshly ready main rat hepatocytes, tanshinones inhibited tolbutamide 4-hydroxylation in a concentration-dependent method, with EC(40) values within the order: cryptotanshinone (15.8microM), tanshinone IIA (16.2microM), dihydrotanshinone (20.1microM) and tanshinone I (48.2microM).

In entire animal research, single dose Danshen remedy (50 or 200mg/kg, i.p.) elevated tolbutamide clearance (17-26.9%), decreased AUC (14.4-20.9%) and elevated the Vd (7.26%). Three-day Danshen remedy (200mg/kg/day, i.p.) decreased the C(preliminary), elevated T(half of) and Vd however didn’t have an effect on tolbutamide clearance and AUC. Tolbutamide-4-hydroxylation in vivo was decreased by Danshen after acute and after 3-day remedy, with decreases within the AUC of 4-hydroxy-tolbutamide (15-28%) over the time interval studied. Regardless of aggressive inhibition of rat CYP2C11 in vitro and in vivo, as proven by the lower in tolbutamide 4-hydroxylation, solely minor modifications in tolbutamide pharmacokinetics was noticed.

Earlier research advised that lamotrigene (LTG) underwent bioactivation to a reactive aryl epoxide intermediate in rats. However, definitive constructions of those thioether conjugates, which are sometimes wanted to substantiate the mechanism of bioactivation and id of reactive intermediate(s), weren’t absolutely established. Within the current examine, GSH, cysteinylglycine, and N-acetyl cysteine conjugates of LTG have been remoted from bile of rats orally dosed with LTG (100 mg/kg), and their constructions have been absolutely elucidated by LC/MS and NMR.

The definitive structural characterization of those metabolites supplied proof for the existence of a reactive aryl epoxide that was trapped as a GSH adduct. In vitro research utilizing varied hepatic mobile and subcellular fractions obtained from human and rat have been carried out to reveal that LTG underwent bioactivation to type a GSH conjugate that was equivalent to the one initially characterised from in vivo research. This examine illustrated that the herb-drug interplay potential must be monitored by each in vitro and in vivo biotransformation/ pharmacokinetic parameters.

In vitro glucuronidation of two,2-bis(bromomethyl)-1,3-propanediol by microsomes and hepatocytes from rats and people.

2,2-Bis(bromomethyl)-1,3-propanediol (BMP) is a brominated flame retardant utilized in unsaturated polyester resins. In a 2-year bioassay BMP was proven to be a multisite carcinogen in rats and mice. As a result of glucuronidation is the important thing metabolic transformation of BMP by rats, on this examine the in vitro hepatic glucuronidation of BMP was in contrast throughout a number of species. As well as, the glucuronidation actions of human intestinal microsomes and particular human hepatic UDP-glucuronosyltransferase (UGT) enzymes for BMP have been decided. To discover different potential routes of metabolism for BMP, research have been performed with rat and human hepatocytes.

Incubation of hepatic microsomes with BMP within the presence of UDP-glucuronic acid resulted within the formation of a BMP monoglucuronide. The order of hepatic microsomal glucuronidation exercise of BMP was rats, mice>>) hamsters>> monkeys>>>> people. The speed of glucuronidation by rat hepatic microsomes was 90-fold larger than that of human hepatic microsomes. Human intestinal microsomes transformed BMP to BMP glucuronide at a charge even decrease than that of human hepatic microsomes. Among the many human UGT enzymes examined, solely UGT2B7 had detectable glucuronidation exercise for BMP.

Pharmacokinetic interaction studies of tanshinones with tolbutamide, a model CYP2C11 probe substrate, using liver microsomes, primary hepatocytes and in vivo in the rat.

BMP monoglucuronide was the one metabolite fashioned when BMP was incubated with suspensions of freshly remoted hepatocytes from male F-344 rats or with cryopreserved human hepatocytes. Glucuronidation of BMP in human hepatocytes was extraordinarily low. General, the outcomes assist in vivo research in rats by which BMP glucuronide was the one metabolite discovered. The poor glucuronidation capability of people for BMP means that the pharmacokinetic profile of BMP in people shall be dramatically completely different from that of rodents.

Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes.

The metabolism and lively transport of ritonavir and saquinavir have been studied utilizing sandwich-cultured rat hepatoyctes and rat liver microsomes. For ritonavir 4 comparable metabolites have been noticed within the sandwich-culture and in microsomes. For saquinavir eight metabolites have been noticed in sandwich-culture and 14 completely different metabolites in microsomes. Ketoconazole didn’t have an effect on the metabolism of ritonavir in sandwich-culture or microsomes and barely inhibited the metabolism of saquinavir in sandwich-culture. This inhibition resulted in a distinct metabolite profile for saquinavir in microsomes. Ritonavir had a pronounced inhibiting impact on the metabolism of saquinavir and affected the hydroxylation of 6beta-testosterone negatively.

Within the lively transport research, cyclosporin A and PSC833 enhanced the metabolism of ritonavir, suggesting that ritonavir is generally excreted into the bile canaliculi. Verapamil, confirmed no impact on the metabolism of ritonavir. The intrinsic clearance was estimated at 1.65 and 67.5 microl/min/1 x 10(6) cells and the hepatic metabolism clearance at 0.017 and 6.83ml/min/SRW for ritonavir and saquinavir respectively. In conclusion, for saquinavir the metabolism charge and the quantity of metabolites produced was greater than for ritonavir.

Microsomes Pyridine, Male Rat Liver

MBS657657-5x02mg 5x0.2mg
EUR 2345

Microsomes Clofibrate, Male Rat liver

MBS657660-02mg 0.2mg
EUR 570

Microsomes Clofibrate, Male Rat liver

MBS657660-5x02mg 5x0.2mg
EUR 2345

Microsomes, Pyridine Induced Rat Liver

MBS480527-02mg 0.2mg
EUR 170

Microsomes, Pyridine Induced Rat Liver

MBS480527-5x02mg 5x0.2mg
EUR 560

MIcrosomes Dexamethasone, Male Rat Liver

MBS657658-02mg 0.2mg
EUR 570

MIcrosomes Dexamethasone, Male Rat Liver

MBS657658-5x02mg 5x0.2mg
EUR 2345

Microsomes, Clofibrate Induced Rat Liver

MBS480526-02mg 0.2mg
EUR 170

Microsomes, Clofibrate Induced Rat Liver

MBS480526-5x02mg 5x0.2mg
EUR 560

Microsomes, Dexamethasone Induced Rat Liver

MBS480528-02mg 0.2mg
EUR 170

Microsomes, Dexamethasone Induced Rat Liver

MBS480528-5x02mg 5x0.2mg
EUR 560

Microsomes 3, Methylcholanthrene, Male Rat Liver

MBS657659-02mg 0.2mg
EUR 570

Microsomes 3, Methylcholanthrene, Male Rat Liver

MBS657659-5x02mg 5x0.2mg
EUR 2345

Microsomes, 3-Methylcholanthrene Ind. Rat Liver

MBS480529-02mg 0.2mg
EUR 170

Microsomes, 3-Methylcholanthrene Ind. Rat Liver

MBS480529-5x02mg 5x0.2mg
EUR 560

Human Antibodies Liver Kidney microsomes,Anti-LKM-1 ELISA KIT

ED0575Hu 96 wells
EUR 458

Bovine Liver kidney microsome autoantibody ELISA kit

E01A84135 96T
EUR 700
Description: ELISA

Bovine Liver Kidney Microsome Autoantibody ELISA Kit

MBS020029-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine Liver Kidney Microsome Autoantibody ELISA Kit

MBS020029-48StripWells 48-Strip-Wells
EUR 550

Bovine Liver Kidney Microsome Autoantibody ELISA Kit

MBS020029-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine Liver Kidney Microsome Autoantibody ELISA Kit

MBS020029-96StripWells 96-Strip-Wells
EUR 765

Bovine Liver kidney microsome autoantibody ELISA Kit

MBS735844-10x96StripWells 10x96-Strip-Wells
EUR 5685

Bovine Liver kidney microsome autoantibody ELISA Kit

MBS735844-48StripWells 48-Strip-Wells
EUR 485

Bovine Liver kidney microsome autoantibody ELISA Kit

MBS735844-5x96StripWells 5x96-Strip-Wells
EUR 3020

Bovine Liver kidney microsome autoantibody ELISA Kit

MBS735844-96StripWells 96-Strip-Wells
EUR 690

Bovine liver/kidney microsomal autoantibody(LKM) ELISA Kit

MBS2609431-10x96StripWells 10x96-Strip-Wells
EUR 3545

Bovine liver/kidney microsomal autoantibody(LKM) ELISA Kit

MBS2609431-48StripWells 48-Strip-Wells
EUR 310

Bovine liver/kidney microsomal autoantibody(LKM) ELISA Kit

MBS2609431-5x96StripWells 5x96-Strip-Wells
EUR 1940

Bovine liver/kidney microsomal autoantibody(LKM) ELISA Kit

MBS2609431-96StripWells 96-Strip-Wells
EUR 475

Bovine liver/kidney microsomal autoantibody(LKM) ELISA Kit

EIA05971Bo each
EUR 520

Bovine Liver/kidney microsomal autoAnti-body(LKM) ELISA Kit

NSL0528Bo 96 T
EUR 528

Microsomes, Ram Seminal Vessicles

MBS480530-5mg 5mg
EUR 300

Microsomes, Ram Seminal Vessicles

MBS480530-5x5mg 5x5mg
EUR 1115

Human Anti-Liver-Kidney Microsomes-1 IgG(Anti-LKM-1 IgG) ELISA KIT

ED0583Hu 96 wells
EUR 458

Human Anti-Liver-Kidney Microsomes-1 IgG (Anti-LKM-1 IgG) ELISA Kit

MBS1610823-10x96StripWells 10x96-Strip-Wells
EUR 3460

Human Anti-Liver-Kidney Microsomes-1 IgG (Anti-LKM-1 IgG) ELISA Kit

MBS1610823-5x96StripWells 5x96-Strip-Wells
EUR 1750

Human Anti-Liver-Kidney Microsomes-1 IgG (Anti-LKM-1 IgG) ELISA Kit

MBS1610823-96StripWells 96-Strip-Wells
EUR 425

Rat Liver kidney microsome autoantibody ELISA kit

E02L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Liver kidney microsome autoantibody ELISA kit

E02L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Liver kidney microsome autoantibody ELISA kit

E02L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Liver kidney microsome autoantibody ELISA kit

E07L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Liver kidney microsome autoantibody ELISA kit

E07L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Liver kidney microsome autoantibody ELISA kit

E07L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Liver kidney microsome autoantibody ELISA kit

E08L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Liver kidney microsome autoantibody ELISA kit

E08L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Liver kidney microsome autoantibody ELISA kit

E08L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Liver kidney microsome autoantibody ELISA kit

E01A14360 96T
EUR 700
Description: ELISA

Cat Liver Kidney Microsome Autoantibody ELISA Kit

MBS107044-INQUIRE INQUIRE Ask for price

Rat Liver Kidney Microsome Autoantibody ELISA Kit

MBS022835-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Liver Kidney Microsome Autoantibody ELISA Kit

MBS022835-48StripWells 48-Strip-Wells
EUR 550

Rat Liver Kidney Microsome Autoantibody ELISA Kit

MBS022835-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Liver Kidney Microsome Autoantibody ELISA Kit

MBS022835-96StripWells 96-Strip-Wells
EUR 765

Rat Liver kidney microsome autoantibody ELISA Kit

MBS730750-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rat Liver kidney microsome autoantibody ELISA Kit

MBS730750-48StripWells 48-Strip-Wells
EUR 485

Rat Liver kidney microsome autoantibody ELISA Kit

MBS730750-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rat Liver kidney microsome autoantibody ELISA Kit

MBS730750-96StripWells 96-Strip-Wells
EUR 690

Goat Liver kidney microsome autoantibody ELISA kit

E01A49268 96T
EUR 700
Description: ELISA

Goat Liver kidney microsome autoantibody ELISA kit

E06L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Liver kidney microsome autoantibody ELISA kit

E06L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Liver kidney microsome autoantibody ELISA kit

E06L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Duck Liver Kidney Microsome Autoantibody ELISA Kit

MBS059258-INQUIRE INQUIRE Ask for price

Goat Liver Kidney Microsome Autoantibody ELISA Kit

MBS026368-INQUIRE INQUIRE Ask for price

Cavy Liver Kidney Microsome Autoantibody ELISA Kit

MBS045911-INQUIRE INQUIRE Ask for price

Fish Liver Kidney Microsome Autoantibody ELISA Kit

MBS034145-INQUIRE INQUIRE Ask for price

Goat Liver kidney microsome autoantibody ELISA Kit

MBS741041-10x96StripWells 10x96-Strip-Wells
EUR 5685

Goat Liver kidney microsome autoantibody ELISA Kit

MBS741041-48StripWells 48-Strip-Wells
EUR 485

Goat Liver kidney microsome autoantibody ELISA Kit

MBS741041-5x96StripWells 5x96-Strip-Wells
EUR 3020

Goat Liver kidney microsome autoantibody ELISA Kit

MBS741041-96StripWells 96-Strip-Wells
EUR 690

Human Liver kidney microsome autoantibody ELISA kit

E01A5612 96T
EUR 700
Description: ELISA

Sheep Liver kidney microsome autoantibody ELISA kit

E01A101561 96T
EUR 700
Description: ELISA

Mouse Liver kidney microsome autoantibody ELISA kit

E01A23105 96T
EUR 700
Description: ELISA

Mouse Liver kidney microsome autoantibody ELISA kit

E03L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Liver kidney microsome autoantibody ELISA kit

E03L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Liver kidney microsome autoantibody ELISA kit

E03L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Camel Liver Kidney Microsome Autoantibody ELISA Kit

MBS104529-INQUIRE INQUIRE Ask for price

Goose Liver Kidney Microsome Autoantibody ELISA Kit

MBS030966-INQUIRE INQUIRE Ask for price

Horse Liver Kidney Microsome Autoantibody ELISA Kit

MBS035136-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Liver Kidney Microsome Autoantibody ELISA Kit

MBS035136-48StripWells 48-Strip-Wells
EUR 550

Horse Liver Kidney Microsome Autoantibody ELISA Kit

MBS035136-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Liver Kidney Microsome Autoantibody ELISA Kit

MBS035136-96StripWells 96-Strip-Wells
EUR 765

Sheep Liver Kidney Microsome Autoantibody ELISA Kit

MBS034523-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep Liver Kidney Microsome Autoantibody ELISA Kit

MBS034523-48StripWells 48-Strip-Wells
EUR 550

Sheep Liver Kidney Microsome Autoantibody ELISA Kit

MBS034523-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep Liver Kidney Microsome Autoantibody ELISA Kit

MBS034523-96StripWells 96-Strip-Wells
EUR 765

Human liver kidney microsome autoantibody ELISA Kit

ELA-E1133h 96tests
EUR 696

Mouse Liver Kidney Microsome Autoantibody ELISA Kit

MBS045939-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Liver Kidney Microsome Autoantibody ELISA Kit

MBS045939-48StripWells 48-Strip-Wells
EUR 550

Mouse Liver Kidney Microsome Autoantibody ELISA Kit

MBS045939-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Liver Kidney Microsome Autoantibody ELISA Kit

MBS045939-96StripWells 96-Strip-Wells
EUR 765

Human Liver Kidney Microsome Autoantibody ELISA Kit

MBS037709-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Liver Kidney Microsome Autoantibody ELISA Kit

MBS037709-48StripWells 48-Strip-Wells
EUR 550

Human Liver Kidney Microsome Autoantibody ELISA Kit

MBS037709-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Liver Kidney Microsome Autoantibody ELISA Kit

MBS037709-96StripWells 96-Strip-Wells
EUR 765

Human Liver kidney microsome autoantibody ELISA Kit

MBS726147-10x96StripWells 10x96-Strip-Wells
EUR 5685

Human Liver kidney microsome autoantibody ELISA Kit

MBS726147-48StripWells 48-Strip-Wells
EUR 485

Human Liver kidney microsome autoantibody ELISA Kit

MBS726147-5x96StripWells 5x96-Strip-Wells
EUR 3020

Human Liver kidney microsome autoantibody ELISA Kit

MBS726147-96StripWells 96-Strip-Wells
EUR 690

Mouse Liver kidney microsome autoantibody ELISA Kit

MBS721014-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Liver kidney microsome autoantibody ELISA Kit

MBS721014-48StripWells 48-Strip-Wells
EUR 485

Mouse Liver kidney microsome autoantibody ELISA Kit

MBS721014-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Liver kidney microsome autoantibody ELISA Kit

MBS721014-96StripWells 96-Strip-Wells
EUR 690

Sheep Liver kidney microsome autoantibody ELISA Kit

MBS739891-10x96StripWells 10x96-Strip-Wells
EUR 5685

Sheep Liver kidney microsome autoantibody ELISA Kit

MBS739891-48StripWells 48-Strip-Wells
EUR 485

Sheep Liver kidney microsome autoantibody ELISA Kit

MBS739891-5x96StripWells 5x96-Strip-Wells
EUR 3020

Sheep Liver kidney microsome autoantibody ELISA Kit

MBS739891-96StripWells 96-Strip-Wells
EUR 690

Rabbit Liver kidney microsome autoantibody ELISA kit

E01A31835 96T
EUR 700
Description: ELISA

Canine Liver kidney microsome autoantibody ELISA kit

E01A66698 96T
EUR 700
Description: ELISA

Rabbit Liver kidney microsome autoantibody ELISA kit

E04L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Liver kidney microsome autoantibody ELISA kit

E04L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Liver kidney microsome autoantibody ELISA kit

E04L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Liver kidney microsome autoantibody ELISA kit

E01A75415 96T
EUR 700
Description: ELISA

Monkey Liver kidney microsome autoantibody ELISA kit

E09L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Liver kidney microsome autoantibody ELISA kit

E09L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Liver kidney microsome autoantibody ELISA kit

E09L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pigeon Liver Kidney Microsome Autoantibody ELISA Kit

MBS104661-INQUIRE INQUIRE Ask for price

Donkey Liver Kidney Microsome Autoantibody ELISA Kit

MBS049304-INQUIRE INQUIRE Ask for price

Canine Liver Kidney Microsome Autoantibody ELISA Kit

MBS022051-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine Liver Kidney Microsome Autoantibody ELISA Kit

MBS022051-48StripWells 48-Strip-Wells
EUR 550

Canine Liver Kidney Microsome Autoantibody ELISA Kit

MBS022051-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine Liver Kidney Microsome Autoantibody ELISA Kit

MBS022051-96StripWells 96-Strip-Wells
EUR 765

Rabbit Liver Kidney Microsome Autoantibody ELISA Kit

MBS032070-INQUIRE INQUIRE Ask for price

Monkey Liver Kidney Microsome Autoantibody ELISA Kit

MBS032864-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey Liver Kidney Microsome Autoantibody ELISA Kit

MBS032864-48StripWells 48-Strip-Wells
EUR 550

Monkey Liver Kidney Microsome Autoantibody ELISA Kit

MBS032864-5x96StripWells 5x96-Strip-Wells
EUR 3420

Monkey Liver Kidney Microsome Autoantibody ELISA Kit

MBS032864-96StripWells 96-Strip-Wells
EUR 765

Rabbit Liver kidney microsome autoantibody ELISA Kit

MBS728446-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rabbit Liver kidney microsome autoantibody ELISA Kit

MBS728446-48StripWells 48-Strip-Wells
EUR 485

Rabbit Liver kidney microsome autoantibody ELISA Kit

MBS728446-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rabbit Liver kidney microsome autoantibody ELISA Kit

MBS728446-96StripWells 96-Strip-Wells
EUR 690

Monkey Liver kidney microsome autoantibody ELISA Kit

MBS742933-10x96StripWells 10x96-Strip-Wells
EUR 5685

Monkey Liver kidney microsome autoantibody ELISA Kit

MBS742933-48StripWells 48-Strip-Wells
EUR 485

Monkey Liver kidney microsome autoantibody ELISA Kit

MBS742933-5x96StripWells 5x96-Strip-Wells
EUR 3020

Monkey Liver kidney microsome autoantibody ELISA Kit

MBS742933-96StripWells 96-Strip-Wells
EUR 690

Canine Liver kidney microsome autoantibody ELISA Kit

MBS741881-10x96StripWells 10x96-Strip-Wells
EUR 5685

Canine Liver kidney microsome autoantibody ELISA Kit

MBS741881-48StripWells 48-Strip-Wells
EUR 485

Canine Liver kidney microsome autoantibody ELISA Kit

MBS741881-5x96StripWells 5x96-Strip-Wells
EUR 3020

Canine Liver kidney microsome autoantibody ELISA Kit

MBS741881-96StripWells 96-Strip-Wells
EUR 690

Porcine Liver kidney microsome autoantibody ELISA kit

E01A57986 96T
EUR 700
Description: ELISA

Chicken Liver kidney microsome autoantibody ELISA kit

E01A92853 96T
EUR 700
Description: ELISA

Chicken Liver Kidney Microsome Autoantibody ELISA Kit

MBS020307-INQUIRE INQUIRE Ask for price

Hamster Liver Kidney Microsome Autoantibody ELISA Kit

MBS013025-10x96StripWells 10x96-Strip-Wells
EUR 6725

Hamster Liver Kidney Microsome Autoantibody ELISA Kit

MBS013025-48StripWells 48-Strip-Wells
EUR 550

Hamster Liver Kidney Microsome Autoantibody ELISA Kit

MBS013025-5x96StripWells 5x96-Strip-Wells
EUR 3420

Hamster Liver Kidney Microsome Autoantibody ELISA Kit

MBS013025-96StripWells 96-Strip-Wells
EUR 765

Porcine Liver Kidney Microsome Autoantibody ELISA Kit

MBS026633-10x96StripWells 10x96-Strip-Wells
EUR 6725

Porcine Liver Kidney Microsome Autoantibody ELISA Kit

MBS026633-48StripWells 48-Strip-Wells
EUR 550

Porcine Liver Kidney Microsome Autoantibody ELISA Kit

MBS026633-5x96StripWells 5x96-Strip-Wells
EUR 3420

Porcine Liver Kidney Microsome Autoantibody ELISA Kit

MBS026633-96StripWells 96-Strip-Wells
EUR 765

Porcine Liver kidney microsome autoantibody ELISA Kit

MBS741327-10x96StripWells 10x96-Strip-Wells
EUR 5685

Porcine Liver kidney microsome autoantibody ELISA Kit

MBS741327-48StripWells 48-Strip-Wells
EUR 485

Porcine Liver kidney microsome autoantibody ELISA Kit

MBS741327-5x96StripWells 5x96-Strip-Wells
EUR 3020

Porcine Liver kidney microsome autoantibody ELISA Kit

MBS741327-96StripWells 96-Strip-Wells
EUR 690

Chicken Liver kidney microsome autoantibody ELISA Kit

MBS741660-10x96StripWells 10x96-Strip-Wells
EUR 5685

Chicken Liver kidney microsome autoantibody ELISA Kit

MBS741660-48StripWells 48-Strip-Wells
EUR 485

Chicken Liver kidney microsome autoantibody ELISA Kit

MBS741660-5x96StripWells 5x96-Strip-Wells
EUR 3020

Chicken Liver kidney microsome autoantibody ELISA Kit

MBS741660-96StripWells 96-Strip-Wells
EUR 690

Mouse Liver Kidney Microsome Autoantibody 1 ELISA Kit

MBS3806692-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Liver Kidney Microsome Autoantibody 1 ELISA Kit

MBS3806692-48StripWells 48-Strip-Wells
EUR 550

Mouse Liver Kidney Microsome Autoantibody 1 ELISA Kit

MBS3806692-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Liver Kidney Microsome Autoantibody 1 ELISA Kit

MBS3806692-96StripWells 96-Strip-Wells
EUR 765

Human liver kidney microsome autoantibody,LKM ELISA Kit

CN-03585H1 96T
EUR 560.4

Human liver kidney microsome autoantibody,LKM ELISA Kit

CN-03585H2 48T
EUR 379.2

Human liver kidney microsome autoantibody,LKM ELISA Kit

YLA1220HU-48T 48T Ask for price

Human liver kidney microsome autoantibody,LKM ELISA Kit

YLA1220HU-96T 96T Ask for price

Human liver kidney microsome autoantibody(LKM)ELISA Kit

GA-E0583HM-48Tests 48 Tests Ask for price

Human liver kidney microsome autoantibody(LKM)ELISA Kit

GA-E0583HM-96Tests 96 Tests
EUR 388

Human liver kidney microsome autoantibody(LKM)ELISA Kit

GA-E0583HM-48T 48T
EUR 346.8

Human liver kidney microsome autoantibody(LKM)ELISA Kit

GA-E0583HM-96T 96T
EUR 559.2

Human liver kidney microsome autoantibody(LKM)ELISA Kit

QY-E02647 96T
EUR 472.8

Human liver kidney microsome autoantibody,LKM ELISA Kit

SL1088Hu 96 Tests
EUR 468

Human Liver Kidney Microsome Autoantibody (LKM) ELISA Kit

MBS3800844-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Liver Kidney Microsome Autoantibody (LKM) ELISA Kit

MBS3800844-48StripWells 48-Strip-Wells
EUR 550

Human Liver Kidney Microsome Autoantibody (LKM) ELISA Kit

MBS3800844-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Liver Kidney Microsome Autoantibody (LKM) ELISA Kit

MBS3800844-96StripWells 96-Strip-Wells
EUR 765

Human liver kidney microsome autoantibody,LKM ELISA Kit

201-12-0567 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Guinea Pig Liver kidney microsome autoantibody ELISA kit

E01A40548 96T
EUR 700
Description: ELISA

Guinea pig Liver kidney microsome autoantibody ELISA kit

E05L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Liver kidney microsome autoantibody ELISA kit

E05L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Liver kidney microsome autoantibody ELISA kit

E05L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Liver kidney microsome autoantibody ELISA Kit

MBS720222-10x96StripWells 10x96-Strip-Wells
EUR 5685

Guinea pig Liver kidney microsome autoantibody ELISA Kit

MBS720222-48StripWells 48-Strip-Wells
EUR 485

Guinea pig Liver kidney microsome autoantibody ELISA Kit

MBS720222-5x96StripWells 5x96-Strip-Wells
EUR 3020

Guinea pig Liver kidney microsome autoantibody ELISA Kit

MBS720222-96StripWells 96-Strip-Wells
EUR 690

Human liver kidney microsome autoantibody,LKM Ab ELISA KIT

E0566Hu-1096T 10*96T
EUR 4122

Human liver kidney microsome autoantibody,LKM Ab ELISA KIT

E0566Hu-48wells 48 wells
EUR 300

Human liver kidney microsome autoantibody,LKM Ab ELISA KIT

E0566Hu-596T 5*96T
EUR 2061

Human liver kidney microsome autoantibody,LKM Ab ELISA KIT

E0566Hu-96wells 96 wells
EUR 458

Human liver kidney microsome type 1 antibody(IgG) Elisa Kit

EK714243 96 Wells
EUR 0.44

Human liver kidney microsome type 1 antibody(IgG) ELISA Kit

CSB-E09074h-24T 1 plate of 24 wells
EUR 198
Description: Qualitativeindirect ELISA kit for measuring Human liver kidney microsome type 1 antibody (IgG) in samples from serum. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human liver kidney microsome type 1 antibody(IgG) ELISA Kit

1-CSB-E09074h
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitativeindirect ELISA kit for measuring Human liver kidney microsome type 1 antibody(IgG) in samples from serum. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human liver kidney microsome type 1 antibody,IgG ELISA KIT

ED0355Hu 96 wells
EUR 458

Human liver kidney microsome type 1 antibody, IgG ELISA Kit

MBS1610674-10x96StripWells 10x96-Strip-Wells
EUR 3460

Human liver kidney microsome type 1 antibody, IgG ELISA Kit

MBS1610674-5x96StripWells 5x96-Strip-Wells
EUR 1750

Human liver kidney microsome type 1 antibody, IgG ELISA Kit

MBS1610674-96StripWells 96-Strip-Wells
EUR 425

Plant Liver Kidney Microsome Autoantibody (Anti-LKM) ELISA Kit

MBS9372735-INQUIRE INQUIRE Ask for price

Mouse Liver Kidney Microsome Autoantibody (Anti-LKM) ELISA Kit

MBS3807100-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Liver Kidney Microsome Autoantibody (Anti-LKM) ELISA Kit

MBS3807100-48StripWells 48-Strip-Wells
EUR 550

Ritonavir had a powerful inhibitory impact on the metabolism of saquinavir and gave the impression to be excreted into the bile. The precise mechanism liable for GSH depletion is unknown at current. Additional experiments are wanted to completely perceive the consequences of BNZs on the parasite GSH analogue, trypanothione, which can be a direct or oblique goal for these brokers. Pharmacokinetic analysis of those compounds is required to additional progress their improvement as potential new remedies for leishmaniasis.

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