Pharmacokinetic interaction studies of tanshinones with tolbutamide, a model CYP2C11 probe substrate, using liver microsomes, primary hepatocytes and in vivo in the rat.

Pharmacokinetic interaction studies of tanshinones with tolbutamide, a model CYP2C11 probe substrate, using liver microsomes, primary hepatocytes and in vivo in the rat. post thumbnail image

The results of Danshen and its lively parts (tanshinone I, tanshinone IIA, dihydrotanshinone and cryptotanshinone) on tolbutamide 4-hydroxylation was investigated within the rat. Danshen (0.125-2mg/ml) decreased 4-hydroxy-tolbutamide formation in vitro and in vivo. Enzyme kinetics research confirmed that inhibition of tolbutamide 4-hydroxylase exercise was aggressive and concentration-dependent. The Ok(i) values of the tanshinones have been: dihydrotanshinone (8.92microM), cryptotanshinone (24.5microM), tanshinone I (80.3microM) and tanshinone IIA (242.9microM). In freshly ready main rat hepatocytes, tanshinones inhibited tolbutamide 4-hydroxylation in a concentration-dependent method, with EC(40) values within the order: cryptotanshinone (15.8microM), tanshinone IIA (16.2microM), dihydrotanshinone (20.1microM) and tanshinone I (48.2microM).

In entire animal research, single dose Danshen remedy (50 or 200mg/kg, i.p.) elevated tolbutamide clearance (17-26.9%), decreased AUC (14.4-20.9%) and elevated the Vd (7.26%). Three-day Danshen remedy (200mg/kg/day, i.p.) decreased the C(preliminary), elevated T(half of) and Vd however didn’t have an effect on tolbutamide clearance and AUC. Tolbutamide-4-hydroxylation in vivo was decreased by Danshen after acute and after 3-day remedy, with decreases within the AUC of 4-hydroxy-tolbutamide (15-28%) over the time interval studied. Regardless of aggressive inhibition of rat CYP2C11 in vitro and in vivo, as proven by the lower in tolbutamide 4-hydroxylation, solely minor modifications in tolbutamide pharmacokinetics was noticed.

Earlier research advised that lamotrigene (LTG) underwent bioactivation to a reactive aryl epoxide intermediate in rats. However, definitive constructions of those thioether conjugates, which are sometimes wanted to substantiate the mechanism of bioactivation and id of reactive intermediate(s), weren’t absolutely established. Within the current examine, GSH, cysteinylglycine, and N-acetyl cysteine conjugates of LTG have been remoted from bile of rats orally dosed with LTG (100 mg/kg), and their constructions have been absolutely elucidated by LC/MS and NMR.

The definitive structural characterization of those metabolites supplied proof for the existence of a reactive aryl epoxide that was trapped as a GSH adduct. In vitro research utilizing varied hepatic mobile and subcellular fractions obtained from human and rat have been carried out to reveal that LTG underwent bioactivation to type a GSH conjugate that was equivalent to the one initially characterised from in vivo research. This examine illustrated that the herb-drug interplay potential must be monitored by each in vitro and in vivo biotransformation/ pharmacokinetic parameters.

In vitro glucuronidation of two,2-bis(bromomethyl)-1,3-propanediol by microsomes and hepatocytes from rats and people.

2,2-Bis(bromomethyl)-1,3-propanediol (BMP) is a brominated flame retardant utilized in unsaturated polyester resins. In a 2-year bioassay BMP was proven to be a multisite carcinogen in rats and mice. As a result of glucuronidation is the important thing metabolic transformation of BMP by rats, on this examine the in vitro hepatic glucuronidation of BMP was in contrast throughout a number of species. As well as, the glucuronidation actions of human intestinal microsomes and particular human hepatic UDP-glucuronosyltransferase (UGT) enzymes for BMP have been decided. To discover different potential routes of metabolism for BMP, research have been performed with rat and human hepatocytes.

Incubation of hepatic microsomes with BMP within the presence of UDP-glucuronic acid resulted within the formation of a BMP monoglucuronide. The order of hepatic microsomal glucuronidation exercise of BMP was rats, mice>>) hamsters>> monkeys>>>> people. The speed of glucuronidation by rat hepatic microsomes was 90-fold larger than that of human hepatic microsomes. Human intestinal microsomes transformed BMP to BMP glucuronide at a charge even decrease than that of human hepatic microsomes. Among the many human UGT enzymes examined, solely UGT2B7 had detectable glucuronidation exercise for BMP.

Pharmacokinetic interaction studies of tanshinones with tolbutamide, a model CYP2C11 probe substrate, using liver microsomes, primary hepatocytes and in vivo in the rat.

BMP monoglucuronide was the one metabolite fashioned when BMP was incubated with suspensions of freshly remoted hepatocytes from male F-344 rats or with cryopreserved human hepatocytes. Glucuronidation of BMP in human hepatocytes was extraordinarily low. General, the outcomes assist in vivo research in rats by which BMP glucuronide was the one metabolite discovered. The poor glucuronidation capability of people for BMP means that the pharmacokinetic profile of BMP in people shall be dramatically completely different from that of rodents.

Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes.

The metabolism and lively transport of ritonavir and saquinavir have been studied utilizing sandwich-cultured rat hepatoyctes and rat liver microsomes. For ritonavir 4 comparable metabolites have been noticed within the sandwich-culture and in microsomes. For saquinavir eight metabolites have been noticed in sandwich-culture and 14 completely different metabolites in microsomes. Ketoconazole didn’t have an effect on the metabolism of ritonavir in sandwich-culture or microsomes and barely inhibited the metabolism of saquinavir in sandwich-culture. This inhibition resulted in a distinct metabolite profile for saquinavir in microsomes. Ritonavir had a pronounced inhibiting impact on the metabolism of saquinavir and affected the hydroxylation of 6beta-testosterone negatively.

Within the lively transport research, cyclosporin A and PSC833 enhanced the metabolism of ritonavir, suggesting that ritonavir is generally excreted into the bile canaliculi. Verapamil, confirmed no impact on the metabolism of ritonavir. The intrinsic clearance was estimated at 1.65 and 67.5 microl/min/1 x 10(6) cells and the hepatic metabolism clearance at 0.017 and 6.83ml/min/SRW for ritonavir and saquinavir respectively. In conclusion, for saquinavir the metabolism charge and the quantity of metabolites produced was greater than for ritonavir.

Rat Liver kidney microsome autoantibody ELISA kit

E02L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Liver kidney microsome autoantibody ELISA kit

E08L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Liver kidney microsome autoantibody ELISA kit

E08L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Liver kidney microsome autoantibody ELISA kit

E08L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Liver kidney microsome autoantibody ELISA kit

E07L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Liver kidney microsome autoantibody ELISA kit

E07L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Liver kidney microsome autoantibody ELISA kit

E07L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Liver kidney microsome autoantibody ELISA kit

E01A49268 96T
EUR 700
Description: ELISA

Goat Liver kidney microsome autoantibody ELISA kit

E06L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Liver kidney microsome autoantibody ELISA kit

E06L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Liver kidney microsome autoantibody ELISA kit

E06L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep Liver kidney microsome autoantibody ELISA kit

E01A101561 96T
EUR 700
Description: ELISA

Human Liver kidney microsome autoantibody ELISA kit

E01A5612 96T
EUR 700
Description: ELISA

Mouse Liver kidney microsome autoantibody ELISA kit

E03L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Liver kidney microsome autoantibody ELISA kit

E03L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Liver kidney microsome autoantibody ELISA kit

E03L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Liver kidney microsome autoantibody ELISA kit

E01L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human liver kidney microsome autoantibody ELISA Kit

ELA-E1133h 96 Tests
EUR 988.8

Mouse Liver kidney microsome autoantibody ELISA kit

E01A23105 96T
EUR 700
Description: ELISA

Canine Liver kidney microsome autoantibody ELISA kit

E01A66698 96T
EUR 700
Description: ELISA

Rabbit Liver kidney microsome autoantibody ELISA kit

E01A31835 96T
EUR 700
Description: ELISA

Monkey Liver kidney microsome autoantibody ELISA kit

E01A75415 96T
EUR 700
Description: ELISA

Monkey Liver kidney microsome autoantibody ELISA kit

E09L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Liver kidney microsome autoantibody ELISA kit

E09L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Liver kidney microsome autoantibody ELISA kit

E09L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Liver kidney microsome autoantibody ELISA kit

E04L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Liver kidney microsome autoantibody ELISA kit

E04L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Liver kidney microsome autoantibody ELISA kit

E04L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Porcine Liver kidney microsome autoantibody ELISA kit

E01A57986 96T
EUR 700
Description: ELISA

Chicken Liver kidney microsome autoantibody ELISA kit

E01A92853 96T
EUR 700
Description: ELISA

Human liver kidney microsome autoantibody,LKM ELISA Kit

201-12-0567 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human liver kidney microsome autoantibody(LKM)ELISA Kit

GA-E0583HM-48T 48T
EUR 346.8

Human liver kidney microsome autoantibody(LKM)ELISA Kit

GA-E0583HM-96T 96T
EUR 559.2

Human liver kidney microsome autoantibody,LKM ELISA Kit

CN-03585H1 96T
EUR 560.4

Human liver kidney microsome autoantibody,LKM ELISA Kit

CN-03585H2 48T
EUR 379.2

Human liver kidney microsome autoantibody(LKM)ELISA Kit

QY-E02647 96T
EUR 472.8

Human liver kidney microsome autoantibody,LKM ELISA Kit

SL1088Hu 96 Tests
EUR 468

Human liver kidney microsome autoantibody,LKM ELISA Kit

YLA1220HU-48T 48T Ask for price

Human liver kidney microsome autoantibody,LKM ELISA Kit

YLA1220HU-96T 96T Ask for price

Bovine Live microsomal autoAnti-body(LMA) ELISA Kit

NSL0529Bo 96 T
EUR 528

Guinea Pig Liver kidney microsome autoantibody ELISA kit

E01A40548 96T
EUR 700
Description: ELISA

Guinea pig Liver kidney microsome autoantibody ELISA kit

E05L0238-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Liver kidney microsome autoantibody ELISA kit

E05L0238-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Liver kidney microsome autoantibody ELISA kit

E05L0238-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Liver kidney microsome autoantibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human liver kidney microsome type 1 antibody(IgG) Elisa Kit

EK714243 96 Wells
EUR 0.44

Human liver kidney microsome type 1 antibody(IgG) ELISA Kit

CSB-E09074h-24T 1 plate of 24 wells
EUR 198
Description: Qualitativeindirect ELISA kit for measuring Human liver kidney microsome type 1 antibody (IgG) in samples from serum. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human liver kidney microsome type 1 antibody(IgG) ELISA Kit

1-CSB-E09074h
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitativeindirect ELISA kit for measuring Human liver kidney microsome type 1 antibody(IgG) in samples from serum. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bovine Anti Thyroid Microsome Antibody ELISA kit

E01A78688 96T
EUR 700
Description: ELISA

Liver Kidney Microsome Type 1 Antibody (IgG) (Human) ELISA Kit (OKCA00483)

OKCA00483 96 Wells
EUR 1030.8
Description: Description of target: Liver Kidney Microsome Type 1 Antibody (IgG);Species reactivity: Human;Application: ;Assay info: Assay Methodology: Qualitative Reverse Capture ELISA;Sensitivity:

Bovine Anti-Thyroid Microsome Antibody(ATMA) Elisa Kit

EK760646 96 Wells
EUR 0.93

Bovine Anti-Thyroid Microsome Anti-body(ATMA) ELISA Kit

NSL1960Bo 96 T
EUR 528

Adenosinetriphosphatase -ATPase- Activity Assay Kit -Cell Membranes, Mitochondria, Microsomes Samples-

E-BC-K039-S-100Assays 100 Assays
EUR 260
Description: Enzyme Activity

Adenosinetriphosphatase -ATPase- Activity Assay Kit -Cell Membranes, Mitochondria, Microsomes Samples-

E-BC-K039-S-50Assays 50 Assays
EUR 18
Description: Enzyme Activity

Adenosinetriphosphatase -ATPase- Activity Assay Kit -Cell Membranes, Mitochondria, Microsomes Samples-

E-BC-K039-S-each each Ask for price
Description: Enzyme Activity

Bovine Liver Genomic DNA

BG-314 0.1mg
EUR 177

Bovine Liver cDNA

BD-314 30 reactions
EUR 243

BOVINE, LIVER, FRESH

8600835 1EA
EUR 86.13

BOVINE, LIVER, FROZEN

8620835 1EA
EUR 86.13

Rat Liver/kidney microsomal autoAnti-body(LKM) ELISA Kit

NSL0375r 96 Tests
EUR 498

Human liver/kidney microsomal auto antibody(LKM) ELISA Kit

NSL1876Hu 96 wells
EUR 468

Goat Liver/kidney microsomal autoAnti-body(LKM) ELISA Kit

NSL0490Gt 96T
EUR 528

Canine Liver/kidney microsomal autoAnti-body(LKM) ELISA Kit

NSL0588Ca 683 wells
EUR 528

Porcine Liver/kidney microsomal autoAnti-body(LKM) ELISA Kit

NSL0409Po 96T
EUR 528

Chicken Liver/kidney microsomal autoAnti-body(LKM) ELISA Kit

NSL0566Ch 661 T
EUR 528

Guinea pig Liver/kidney microsomal autoAnti-body(LKM) ELISA Kit

NSL0564Gp 96T
EUR 528

Bovine Liver Total RNA

BR-314 0.1mg
EUR 160

Catalase from Bovine Liver

07444-74 100MG
EUR 48.3

Bovine Liver Total Protein

BT-314 1mg
EUR 153

Bovine Liver Tissue Lysate

IBOLRTL100UG each
EUR 541
Description: Bovine Liver Tissue Lysate

Bovine Liver Frozen Sections

BF-314 10 slides
EUR 261

OORA00341-10U - BOVINE LIVER

OORA00341-10U 1Each
EUR 250

OORA00341-1EA - BOVINE LIVER

OORA00341-1EA 1Each
EUR 229

Bovine Liver Paraffin Sections

BP-314 10 slides
EUR 240

Bovine Prostaglandin E Synthase, Microsomal ELISA kit

E01A85475 96T
EUR 700
Description: ELISA

Bovine Liver X receptor alpha

E01A84207 96T
EUR 700
Description: ELISA

Bovine Liver glycogen ELISA kit

E01A83517 96T
EUR 700
Description: ELISA

Bovine Microsomal Triglyceride Transfer Protein ELISA kit

E01A84260 96T
EUR 700
Description: ELISA

Catalase (>40,000 u/mg), Bovine Liver

CAT-04 1 mg
EUR 343.2

Anti- Catalase (Bovine Liver) Antibody

GWB-8A2071 50 mg Ask for price

Anti- Arginase (Bovine Liver) Antibody

GWB-738907 50 mg Ask for price

Anti-CATALASE (Bovine Liver) Antibody

GWB-5B36D2 2 mL Ask for price

Bovine Microsomal glutathione S transferase 1(MGST1) ELISA kit

E01A84473 96T
EUR 700
Description: ELISA

Bovine Microsomal glutathione S- transferase 2, MGST2 ELISA KIT

ELI-38955b 96 Tests
EUR 1113.6

Bovine Microsomal glutathione S- transferase 3, MGST3 ELISA KIT

ELI-23421b 96 Tests
EUR 1113.6

Bovine Microsomal glutathione S- transferase 1, MGST1 ELISA KIT

ELI-20369b 96 Tests
EUR 1113.6

MGST1 ELISA Kit| Bovine Microsomal glutathione S-transferase 1

EF011605 96 Tests
EUR 826.8

Bovine Liver X Receptor ELISA kit

E01A84164 96T
EUR 700
Description: ELISA

Catalase (10,000-15,000 U/mg), Bovine Liver

CAT-01 25 mU
EUR 634.8

Catalase (4000-6000 U/mg), Bovine Liver

CAT-03 5 mU
EUR 416.4

Innovative Grade US Origin Bovine Liver

IGBOLRF each
EUR 133
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRFT1 each
EUR 133
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRFT2 each
EUR 210
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRFT3 each
EUR 210
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRFT4 each
EUR 133
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRP each
EUR 280
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRPT1 each
EUR 356
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRPT2 each
EUR 356
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRPT3 each
EUR 280
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRPT4 each
EUR 133
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRS each
EUR 210
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRST1 each
EUR 210
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRST2 each
EUR 133
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRST3 each
EUR 133
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRST4 each
EUR 210
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRZ each
EUR 210
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRZT1 each
EUR 133
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRZT2 each
EUR 133
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRZT3 each
EUR 210
Description: Innovative Grade US Origin Bovine Liver

Innovative Grade US Origin Bovine Liver

IGBOLRZT4 each
EUR 210
Description: Innovative Grade US Origin Bovine Liver

Bovine Liver specific lipootein ELISA kit

E01A84156 96T
EUR 700
Description: ELISA

Bovine Collectin Liver 1 ELISA kit

E01A80759 96T
EUR 700
Description: ELISA

Bovine Microsomal triglyceride transfer protein large subunit (MTTP) ELISA Kit

EK9111 96Т
EUR 799

Bovine Microsomal triglyceride transfer protein large subunit (MTTP) ELISA Kit

AE32306BO-48Tests 48 Tests
EUR 360
Description: Bovine (Bos taurus; Cattle)

Bovine Microsomal triglyceride transfer protein large subunit (MTTP) ELISA Kit

AE32306BO-96Tests 96 Tests
EUR 680
Description: Bovine (Bos taurus; Cattle)

Bovine MTTP / Microsomal triglyceride transfer protein large subunit ELISA Kit

E1128b 96T
EUR 900

ELISA kit for Bovine Microsomal triglyceride transfer protein large subunit (MTTP)

KTE10243-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Microsomal triglyceride transfer protein large subunit (MTTP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Microsomal triglyceride transfer protein large subunit (MTTP)

KTE10243-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Microsomal triglyceride transfer protein large subunit (MTTP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Microsomal triglyceride transfer protein large subunit (MTTP)

KTE10243-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Microsomal triglyceride transfer protein large subunit (MTTP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Anti-GLUTAMATE DEHYDROGENASE (Bovine Liver) Antibody

GWB-19E2F1 2 mL Ask for price

Bovine Liver specific lipoprotein(LSP) ELISA Kit

NSL0542Bo 96 T
EUR 528

Bovine Arginase 1 (Liver type) ELISA kit

E01A78794 96T
EUR 700
Description: ELISA

Bovine Glycogen Phosphorylase, Liver ELISA kit

E01A85491 96T
EUR 700
Description: ELISA

Bovine Liver Fatty Acid Binding Protein, L-FABP GENLISA ELISA

KLB0367 1 x 96 wells
EUR 341

Human Anti-Liver Kidney Microsome Type 1 IgG (LKM1) ELISA Kit

abx352171-96tests 96 tests
EUR 943.2

Bovine Phosphofructokinase, liver (PFKL) ELISA Kit

SL0061Bo -
EUR 528

Bovine Anti soluble liver antigen ELISA kit

E01A86343 96T
EUR 700
Description: ELISA

Bovine 6-phosphofructokinase, liver type, PFKL GENLISA ELISA

KLB0153 1 x 96 wells
EUR 341

Bovine Augmenter of Liver Regeneration ELISA kit

E01A78583 96T
EUR 700
Description: ELISA

Bovine Anti liver cell membrane antibody ELISA kit

E01A84138 96T
EUR 700
Description: ELISA

Bovine Anti liver cytosolantibody type 1 ELISA kit

E01A84123 96T
EUR 700
Description: ELISA

Bovine Fatty acid-binding protein, liver ELISA Kit

EK4389 96 tests
EUR 639

Bovine Liver Fatty Acid Binding Protein(L-FABP) ELISA Kit

NSL1099Bo 96 T
EUR 528

Bovine Liver expressed antimicrobial peptide 2(LEAP2) ELISA kit

E01A84193 96T
EUR 700
Description: ELISA

Bovine Liver- expressed antimicrobial peptide 2, LEAP2 ELISA KIT

ELI-20184b 96 Tests
EUR 1113.6

Bovine Alkaline Phosphatase, Liver/Bone/Kidney ELISA kit

E01A78658 96T
EUR 700
Description: ELISA

Bovine 6 phosphofructokinase, liver type(PFKL) ELISA kit

E01A85790 96T
EUR 700
Description: ELISA

Bovine Glycogen phosphorylase, liver form (PYGL) ELISA Kit

EK7893 96Т
EUR 799

Bovine Glycogen phosphorylase, liver form, PYGL ELISA KIT

ELI-02892b 96 Tests
EUR 1113.6

Bovine 6- phosphofructokinase, liver type, PFKL ELISA KIT

ELI-03285b 96 Tests
EUR 1113.6

Bovine Glycogen phosphorylase, liver form (PYGL) ELISA Kit

AE24912BO-48Tests 48 Tests
EUR 360
Description: Bovine (Bos taurus; Cattle)

Bovine Glycogen phosphorylase, liver form (PYGL) ELISA Kit

AE24912BO-96Tests 96 Tests
EUR 680
Description: Bovine (Bos taurus; Cattle)

Liver X Receptor Alpha (LXRa) Polyclonal Antibody (Bovine)

4-PAC044Bo01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Liver X Receptor Alpha (LXRa)

Bovine PYGL / Glycogen phosphorylase, liver form ELISA Kit

E0849b 96T
EUR 900

Bovine 6-phosphofructokinase, liver type(PFKL) Elisa kit

EK760178 96 Wells
EUR 0.91

Bovine 6-phosphofructokinase, liver type(PFKL)ELISA kit

YLA0245BO-48T 48T Ask for price

Bovine 6-phosphofructokinase, liver type(PFKL)ELISA kit

YLA0245BO-96T 96T Ask for price

Bovine PFKL / 6-phosphofructokinase, liver type ELISA Kit

E10219b 96T
EUR 900

Gentodenz

19-DENZ-500 500 g
EUR 416

LEAP2 ELISA Kit| Bovine Liver-expressed antimicrobial peptide 2

EF011562 96 Tests
EUR 826.8

Bovine Fatty acid- binding protein, liver, FABP1 ELISA KIT

ELI-07065b 96 Tests
EUR 1113.6

Bovine Liver Type Fatty Acid Binding Protein(L-FABP) ELISA KIT

YLA0328BO-48T 48T Ask for price

Bovine Liver Type Fatty Acid Binding Protein(L-FABP) ELISA KIT

YLA0328BO-96T 96T Ask for price

Bovine FABP1/ Fatty acid-binding protein, liver ELISA Kit

E0092Bo 1 Kit
EUR 630
Description: Fatty acid-binding protein 1,Liver-type fatty acid-binding protein,L-FABP

Bovine Fatty acid-binding protein, liver (FABP1) ELISA Kit

RK15079 96T
EUR 280

Bovine FABP1 / Fatty acid-binding protein, liver ELISA Kit

E2204b 96T
EUR 900

L-FABP ELISA Kit| Bovine Liver Fatty acid Binding Protein ELISA

EF011047 96 Tests
EUR 826.8

Liver X Receptor Alpha (LXRa) Polyclonal Antibody (Bovine), PE

4-PAC044Bo01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Liver X Receptor Alpha (LXRa). This antibody is labeled with PE.

Liver X Receptor Alpha (LXRa) Polyclonal Antibody (Bovine), APC

4-PAC044Bo01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Liver X Receptor Alpha (LXRa). This antibody is labeled with APC.

Liver X Receptor Alpha (LXRa) Polyclonal Antibody (Bovine), Cy3

4-PAC044Bo01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Liver X Receptor Alpha (LXRa). This antibody is labeled with Cy3.

Liver X Receptor Alpha (LXRa) Polyclonal Antibody (Bovine), HRP

4-PAC044Bo01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Liver X Receptor Alpha (LXRa). This antibody is labeled with HRP.

ELISA kit for Bovine Glycogen phosphorylase, liver form (PYGL)

KTE10142-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Glycogen phosphorylase, liver form (PYGL) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Glycogen phosphorylase, liver form (PYGL)

KTE10142-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Glycogen phosphorylase, liver form (PYGL) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Glycogen phosphorylase, liver form (PYGL)

KTE10142-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Glycogen phosphorylase, liver form (PYGL) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Liver X Receptor Alpha (LXRa) Polyclonal Antibody (Bovine), FITC

4-PAC044Bo01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Liver X Receptor Alpha (LXRa). This antibody is labeled with FITC.

Bovine Fatty Acid Binding Protein 1, Liver (FABP1) ELISA Kit

E01A84167 96T
EUR 700
Description: ELISA

Bovine L-FABP(Liver Fatty acid Binding Protein) ELISA Kit

EB0095 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Cattle;Sensitivity: 0.469 ng/ml

Bovine LEAP2 / Liver-expressed antimicrobial peptide 2 ELISA Kit

E13542b 96T
EUR 900

Liver X Receptor Alpha (LXRa) Polyclonal Antibody (Bovine), APC-Cy7

4-PAC044Bo01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Bovine Liver X Receptor Alpha (LXRa). This antibody is labeled with APC-Cy7.

Liver X Receptor Alpha (LXRa) Polyclonal Antibody (Bovine), Biotinylated

4-PAC044Bo01-Biotin
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  • 100ul
  • 10ml
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  • 200ul
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Description: A Rabbit polyclonal antibody against Bovine Liver X Receptor Alpha (LXRa). This antibody is labeled with Biotin.

Fatty Acid Binding Protein 1, Liver (FABP1) Polyclonal Antibody (Bovine)

4-PAB566Bo01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Bovine Fatty Acid Binding Protein 1, Liver (FABP1)

Microsome Isolation Kit

K249-50 each
EUR 633.6

Fatty Acid Binding Protein 1, Liver (FABP1) Polyclonal Antibody (Bovine), PE

4-PAB566Bo01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Fatty Acid Binding Protein 1, Liver (FABP1). This antibody is labeled with PE.

Fatty Acid Binding Protein 1, Liver (FABP1) Polyclonal Antibody (Bovine), APC

4-PAB566Bo01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Fatty Acid Binding Protein 1, Liver (FABP1). This antibody is labeled with APC.

Fatty Acid Binding Protein 1, Liver (FABP1) Polyclonal Antibody (Bovine), Cy3

4-PAB566Bo01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Fatty Acid Binding Protein 1, Liver (FABP1). This antibody is labeled with Cy3.

Fatty Acid Binding Protein 1, Liver (FABP1) Polyclonal Antibody (Bovine), FITC

4-PAB566Bo01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Fatty Acid Binding Protein 1, Liver (FABP1). This antibody is labeled with FITC.

Fatty Acid Binding Protein 1, Liver (FABP1) Polyclonal Antibody (Bovine), HRP

4-PAB566Bo01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Fatty Acid Binding Protein 1, Liver (FABP1). This antibody is labeled with HRP.

50ml TC Tubes, Conical, 440 units/box

04-5540150 440 units/box
EUR 85.2

GMP IL4, 50µg

04-GMP-HU-IL4-50UG 50µg
EUR 579.6
Description: Recombinant Human IL-4 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 130 amino acids and having a molecular mass of 15000 Dalton. The rHuIL-4 is purified by proprietary chromatographic techniques.

SDS-Blue™ - Coomassie based solution for protein staining in SDS-PAGE

04-GSB
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  • 1L
  • 500mL
Description: SDS-Blue™ is an innovative patented formula, based on Coomassie blue, that comes in a convenient ready to use format for staining proteins in SDS-PAGE (sodium dodecyl sulphate–polyacrylamide gel electrophoresis). The formulation of SDS-Blue™ provides numerous advantages compared to the classic Coomassie staining or to other similar protein stains. SDS-Blue™ provides higher sensitivity, virtually no background and eliminates the need for destaining of the gel due to its high specificity and affinity to bind to protein only. Not only does SDS-Blue™ yield clear and sharp bands, but it also contains no methanol and acetic acid, making it non-hazardous, safe to handle and friendly to the environment when disposed of. Two other advantages that make SDS-Blue™ the better option is that it is not light sensitive and can be stored at ambient temperature for 24 months. And this provides a considerable convenience, especially to laboratories that need and keep big amount of protein staining solutions – no more jammed refrigerators, you can keep SDS-Blue™ wherever it is most convenient for You!

rHu IL 2 , 3MIU

04-RHIL2-02F01 1 vial
EUR 298.8
Description: Recombinant human interleukin-2 is a sterile protein product for injection. rHuIL-2 is produced by recombinant DNA technology using Yeast. It is a highly purified protein containing 133 amino acids, with cysteine mutated to alanine at 125 amino acid position, and has a molecular weight of approximately 15.4kD, non-glycosylated.

rHu IL 2 , 3MIU , Lot 200908F02

04-RHIL2-08F02 1 vial
EUR 298.8
Description: Recombinant human interleukin-2 is a sterile protein product for injection. rHuIL-2 is produced by recombinant DNA technology using Yeast. It is a highly purified protein containing 133 amino acids, with cysteine mutated to alanine at 125 amino acid position, and has a molecular weight of approximately 15.4kD, non-glycosylated.

PRE-GMP rHu GM-CSF, Molgramostim-Leukoma

04-RHUGM-CSF-7A10 300 µg
EUR 462
Description: Recombinant human GM-CSF produced in E.coli is a single, non-glycosylated, polypeptide chain containing 127 amino acids, two pairs of disulfide bonds and having a molecular mass of approximately 14.5kD.

QuantiChrom Hemoglobin Assay Kit

65-DIHB-250 250 tests
EUR 473

Malachite Green Phosphate Assay kit

65-POMG-25H 2500 tests
EUR 333

Mouse Anti TNP Immunotoxicity

198-TNPG-1 100 µL
EUR 469.2

Exo-Check Exosome Antibody Array

322-EXO-FBS-50A-1 100 µg
EUR 469.2

Rye Agar A

765-M1854-500G 500 g
EUR 82

Rye Agar B

765-M1855-500G 500 g
EUR 93

Porcine Parvovirus Antibody Elisa Test Kit

767-LSY-30009 192 Wells/kit
EUR 382

1-Step Polymorphs, Human Cell Separation

71-AN221725 1
EUR 238.8

GMP Recombinant Human Interleukin-4 (IL-4)

GMPhuIL-4-50ug 50ug
EUR 528

Monkeypox Virus Real Time PCR Kit

ZD-0076-01 25 tests/kit Ask for price
Description: Monkeypox virus is the virus that causes the disease monkeypox in both humans and animals. Monkeypox virus is an Orthopoxvirus, a genus of the family Poxviridae that contains other viral species that target mammals. The virus is mainly found in tropical rainforest regions of central and West Africa. The primary route of infection is thought to be contact with the infected animals or their bodily fluids. The genome is not segmented and contains a single molecule of linear double-stranded DNA, 185000 nucleotides long. The Monkeypox Virus real time PCR Kit contains a specific ready-to-use system for the detection of the Monkeypox Virusthrough polymerase chain reaction (PCR) in the real-time PCR system. The master contains reagents and enzymes for the specific amplification of the Monkeypox Virus DNA. Fluorescence is emitted and measured by the real time systems ́ optical unit during the PCR. The detection of amplified Monkeypox Virus DNA fragment is performed in fluorimeter channel 530nm with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit and serum or lesion exudate samples are used for the extraction of the DNA. In addition, the kit contains a system to identify possible PCR inhibition by measuring the 560nm fluorescence of the internal control (IC). An external positive control defined as 1×10^7 copies/ml is supplied which allow the determination of the gene load.

Monkeypox Virus Real Time PCR Kit

ZD-0076-02 25 tests/kit Ask for price
Description: Monkeypox virus is the virus that causes the disease monkeypox in both humans and animals. Monkeypox virus is an Orthopoxvirus, a genus of the family Poxviridae that contains other viral species that target mammals. The virus is mainly found in tropical rainforest regions of central and West Africa. The primary route of infection is thought to be contact with the infected animals or their bodily fluids.The genome is not segmented and contains a single molecule of linear double-stranded DNA, 185000 nucleotides long.The Monkeypox Virus real time PCR Kit contains a specific ready-to-use system for the detection of the Monkeypox Virusthrough polymerase chain reaction (PCR) in the real-time PCR system. The master contains reagents and enzymes for the specific amplification of theMonkeypox VirusDNA. Fluorescence is emitted and measured by the real time systems ́ optical unit during the PCR. The detection of amplified Monkeypox Virus DNA fragment is performed in fluorimeter channelFAM with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit and serum or lesion exudate samples are used for the extraction of the DNA. In addition, the kit contains a system to identify possible PCR inhibition by measuring the HEX/VIC/JOE fluorescence of the internal control (IC). An external positive control defined as 1×107copies/ml is supplied which allow the determination of the gene load.

EasyNat Quattro

UC0104 4-module system
EUR 12000

EasyNat Octo

UC0108 8-module system
EUR 22000

Rat Live microsomal autoAnti-body(LMA) ELISA Kit

NSL0377r 96 Tests
EUR 498

Goat Live microsomal autoAnti-body(LMA) ELISA Kit

NSL0489Gt 96T
EUR 528

Bovine Carnitine O palmitoyltransferase 1, liver isoform (CPT1A/CPT1) ELISA kit

E01A82038 96T
EUR 700
Description: ELISA

Ritonavir had a powerful inhibitory impact on the metabolism of saquinavir and gave the impression to be excreted into the bile. The precise mechanism liable for GSH depletion is unknown at current. Additional experiments are wanted to completely perceive the consequences of BNZs on the parasite GSH analogue, trypanothione, which can be a direct or oblique goal for these brokers. Pharmacokinetic analysis of those compounds is required to additional progress their improvement as potential new remedies for leishmaniasis.

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