The in vitro metabolism of rivaroxaban, a novel, oral, direct issue Xa inhibitor for the prevention and remedy of thromboembolic issues, was investigated in a number of species, together with people. The target of this research was to elucidate metabolite constructions and establish the metabolic pathways to offer assist for in vivo security and medical research. [(14)C]Rivaroxaban was incubated with liver microsomes and hepatocytes of rats, canine, and people. The samples had been analyzed by high-performance liquid chromatography-(14)C-tandem mass spectroscopy, to generate metabolite profiles and suggest or affirm the constructions of the metabolites shaped. In vitro metabolite profiles confirmed no main variations between species.
The principle oxidative metabolic pathways recognized for all species had been hydroxylation on the morpholinone moiety (M-2, M-3, and M-8) and to a lesser extent on the oxazolidinone moiety (M-9). M-2 was the primary metabolite in all microsomal incubations. M-1, a morpholinone ring-opened product shaped by additional oxidation of M-2, was the primary metabolite in all hepatocyte incubations. Different pathways had been amide hydrolysis on the morpholinone ring (M-7) and the chlorothiophene amide moiety (M-13 and M-15). In hepatocytes, M-13 was readily conjugated with glycine, resulting in M-4. The metabolic destiny of unlabeled M-15 was investigated individually.
Incubations with human liver microsomes and hepatocytes confirmed that M-15 was first oxidized to the aldehyde intermediate M-16 and subsequently diminished to M-17 (alcohol) or oxidized to M-18 (carboxylic acid). No metabolism on the chlorothiophene moiety itself was discovered. Total, rivaroxaban confirmed no species variations in metabolism, with completely different unbiased metabolic pathways and no formation of reactive metabolites.
In vivo clearance predictions from in vitro assays require scaling elements to narrate the concentrations of hepatocytes or microsomal protein to the intact liver. 2. The goals had been to measure the variability in scaling elements for Wistar rat and beagle canine for which the literature is especially scarce and decide any intercourse variations. 3. Scaling elements had been decided by evaluating the cytochrome P450 (P450) content material in hepatocytes or microsomes in opposition to the P450 content material of recent liver homogenate. Using recent homogenate is really helpful as freezing can improve contamination and have an effect on the P450 assay.
Comparability of genistein metabolism in rats and people utilizing liver microsomes and hepatocytes.
Species variations and metabolism are probably the most essential elements in contemplating the results of genistein. The goal of this research was to have a greater information of the metabolic destiny of genistein in people as in contrast with rats. For this goal, radiolabeled genistein was incubated with human and rat liver microsomes and with cryopreserved hepatocytes from each species. Incubations had been carried out utilizing a variety of genistein concentrations to research the kinetics of formation of the metabolites. Metabolite profiling was obtained utilizing an HPLC system linked to a radioactivity detector.
Identification of the metabolites was primarily based on their retention occasions as in contrast with these of genuine requirements and on LC-MS (ESI-MS/MS) or NMR analyses. In each species, liver microsomes produced the identical three hydroxylated metabolites (8-OH, 6-OH and three’-OH-genistein) whereas cryopreserved hepatocytes produced the identical glucurono- and sulfo-conjugates (genistein 4′-O-sulfate 7-O-glucuronide, genistein 7-O-glucuronide, genistein 4′-O-glucuronide, genistein 7-O-sulfate and genistein 4′-O-sulfate). The speed of metabolism assorted with species. 3′-Hydroxygenistein was the predominant metabolite produced by rat liver microsomes, whereas in people 3′-hydroxy and 8-hydroxygenistein had been produced in the identical vary.
Metabolism of prazosin in rat, canine, and human liver microsomes and cryopreserved rat and human hepatocytes and characterization of metabolites by liquid chromatography/tandem mass spectrometry.
Prazosin (2-[4-(2-furanoyl)-piperazin-1-yl]-4-amino-6,7-dimethoxyquinazoline) is an antihypertensive agent that was launched to the market in 1976. It has since established a wonderful security document. Nonetheless, in vitro metabolism of prazosin has not been investigated. This research describes the in vitro biotransformation of prazosin in liver microsomes from rats, canine, and people, in addition to rat and human cryopreserved hepatocytes and characterization of metabolites utilizing liquid chromatography/tandem mass spectrometry. The main in vivo biotransformation pathways reported beforehand in rats and canine embody demethylation, amide hydrolysis, and O-glucuronidation.
These metabolic pathways had been additionally confirmed in our research. As well as, a number of new metabolites had been characterised, together with a secure carbinolamine, an iminium species, and an enamine-all shaped by way of oxidation of the piperazine ring. Two ring-opened metabolites generated following oxidative cleavage of the furan ring had been additionally recognized. Utilizing semicarbazide hydrochloride as a trapping agent, an intermediate arising from opening of the furan ring was captured as a pyridazine product. Within the presence of glutathione, three glutathione conjugates had been detected in microsomal incubations, though they weren’t detected in cryopreserved hepatocytes.
 (human)) Seminal Plasma Inhibin (67-94) (human) |
|
H-1602.0500 |
Bachem |
0.5mg |
EUR 400.8 |
|
Description: Sum Formula: C150H240N36O43S2; CAS# [96182-95-5] |
Seminal Plasma Inhibin (67-94) (human) |
|
H-1602.1000 |
Bachem |
1.0mg |
EUR 691.2 |
|
Description: Sum Formula: C150H240N36O43S2; CAS# [96182-95-5] |
 Rat Secreted seminal- vesicle Ly- 6 protein 1, Sslp1 ELISA KIT |
|
ELI-42469r |
Lifescience Market |
96 Tests |
EUR 1063.2 |
 Mouse Secreted seminal- vesicle Ly- 6 protein 1, Sslp1 ELISA KIT |
|
ELI-41041m |
Lifescience Market |
96 Tests |
EUR 1038 |
 Bovine Secreted seminal- vesicle Ly- 6 protein 1, SSLP1 ELISA KI |
|
ELI-18704b |
Lifescience Market |
96 Tests |
EUR 1113.6 |
 Porcine Secreted seminal- vesicle Ly- 6 protein 1, SSLP1 ELISA K |
|
ELI-41771p |
Lifescience Market |
96 Tests |
EUR 1113.6 |
 Bovine Seminal ribonuclease, SRN ELISA KIT |
|
ELI-40880b |
Lifescience Market |
96 Tests |
EUR 1113.6 |
 Rat seminal plasma protein homolog 1 ELISA kit |
|
E02B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat seminal plasma protein homolog 1 ELISA kit |
|
E02B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat seminal plasma protein homolog 1 ELISA kit |
|
E02B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Dog seminal plasma protein homolog 1 ELISA kit |
|
E08B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog seminal plasma protein homolog 1 ELISA kit |
|
E08B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog seminal plasma protein homolog 1 ELISA kit |
|
E08B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Pig seminal plasma protein homolog 1 ELISA kit |
|
E07B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig seminal plasma protein homolog 1 ELISA kit |
|
E07B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig seminal plasma protein homolog 1 ELISA kit |
|
E07B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 protein) LTF S.Plasma Lactoferrin Human (Seminal Plasma) protein |
|
PROTP02788-2 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: The Human Lactoferrin produced from pooled Human seminal plasma has a molecular mass of 76.165kDa (calculated without glycosylation) containing 691 amino acid residues. |
 Goat seminal plasma protein homolog 1 ELISA kit |
|
E06B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat seminal plasma protein homolog 1 ELISA kit |
|
E06B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat seminal plasma protein homolog 1 ELISA kit |
|
E06B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Human seminal plasma protein homolog 1 ELISA kit |
|
E01B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human seminal plasma protein homolog 1 ELISA kit |
|
E01B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human seminal plasma protein homolog 1 ELISA kit |
|
E01B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Mouse seminal plasma protein homolog 1 ELISA kit |
|
E03B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse seminal plasma protein homolog 1 ELISA kit |
|
E03B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse seminal plasma protein homolog 1 ELISA kit |
|
E03B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Rabbit seminal plasma protein homolog 1 ELISA kit |
|
E04B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit seminal plasma protein homolog 1 ELISA kit |
|
E04B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit seminal plasma protein homolog 1 ELISA kit |
|
E04B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Monkey seminal plasma protein homolog 1 ELISA kit |
|
E09B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey seminal plasma protein homolog 1 ELISA kit |
|
E09B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey seminal plasma protein homolog 1 ELISA kit |
|
E09B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Pig seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E07S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E07S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E07S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Porcine seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Dog seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E08S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E08S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E08S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Canine seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Rat seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E02S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E02S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E02S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rat seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Guinea pig seminal plasma protein homolog 1 ELISA kit |
|
E05B0856-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig seminal plasma protein homolog 1 ELISA kit |
|
E05B0856-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig seminal plasma protein homolog 1 ELISA kit |
|
E05B0856-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig seminal plasma protein homolog 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Goat seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E06S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E06S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E06S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Goat seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Mouse seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E03S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E03S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E03S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Mouse seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Human seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E01S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E01S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E01S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Monkey seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E09S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E09S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E09S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Monkey seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Rabbit seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E04S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E04S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E04S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Rabbit seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Porcine Seminal plasma sperm motility inhibitor, SPMI ELISA KIT |
|
ELI-41439p |
Lifescience Market |
96 Tests |
EUR 1113.6 |
 ELISA kit) Guinea pig seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E05S0303-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E05S0303-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig seminal plasma protein homolog 1(BSPH1) ELISA kit |
|
E05S0303-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig seminal plasma protein homolog 1(BSPH1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Human Bovine seminal plasma protein homolog 1, BSPH1 ELISA KIT |
|
ELI-33283h |
Lifescience Market |
96 Tests |
EUR 988.8 |
 Mouse Bovine seminal plasma protein homolog 1, Bsph1 ELISA KIT |
|
ELI-50141m |
Lifescience Market |
96 Tests |
EUR 1038 |
 Analog) Seminalplasmin Fragment (SPF) Analog |
|
H-1636.0001 |
Bachem |
1.0mg |
EUR 283.2 |
|
Description: Sum Formula: C76H123N17O16; CAS# [147958-06-3] |
Seminalplasmin Fragment (SPF) Analog |
|
H-1636.0005 |
Bachem |
5.0mg |
EUR 1023.6 |
|
Description: Sum Formula: C76H123N17O16; CAS# [147958-06-3] |
 antiserum # 1) Rabbit Anti-Human PiT2 (GLVR2/Ram-1) antiserum # 1 |
|
PIT21-S |
Alpha Diagnostics |
100 ul |
EUR 548.4 |
 Control/blocking peptide #1) Human PiT2 (GLVR2/Ram-1) Control/blocking peptide #1 |
|
PIT21-P |
Alpha Diagnostics |
100 ug |
EUR 196.8 |
 Ramucirumab (Cyramza)Free drug ELISA kit) Shikari (Q-RAM) Ramucirumab (Cyramza)Free drug ELISA kit |
|
RAM-FD-CYR |
Matriks Biotek |
1x96-wells test plate |
EUR 1053.6 |
|
Description: Enzyme Immunoassay for detection of freeRamucirumab (Cyramza) in human serum and plasma samples. |
 Western blot +ve control) Purified Ram Cyclooxygenase (Cox-1) Western blot +ve control |
|
COX11-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
 Western blot +ve control) Purified Ram Cyclooxygenase (Cox-2) Western blot +ve control |
|
COX21-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
 IgG #1, aff pure) Rabbit Anti-Human PiT2 (GLVR2/Ram-1) IgG #1, aff pure |
|
PIT21-A |
Alpha Diagnostics |
100 ug |
EUR 578.4 |
 IgG #1) Rabbit Anti-Ram Cyclooxygenase (Cox-1) IgG #1 |
|
COX11-A |
Alpha Diagnostics |
100 ul |
EUR 578.4 |
 Testis seminoma and lymphoma tissue array |
|
TE802 |
TissueArray |
each |
EUR 270 |
|
Description: Testis seminoma and lymphoma tissue array, 80 cases/80 cores |
 Paraffin Tissue Section - Human Testis Tumor: Seminoma |
|
T2235260-3 |
Biochain |
5 slides |
EUR 238 |
, Mouse and Rat) Reproductive Tissue Dissociation System 2 (Seminiferous tubules), Mouse and Rat |
|
4-20412 |
CHI Scientific |
ea |
Ask for price |
, Mouse and Rat) Reproductive Tissue Dissociation System 1 (Epithelial,Leydig, Luteal, ovaries, Sertolli, seminiforous tubules), Mouse and Rat |
|
4-20411 |
CHI Scientific |
ea |
Ask for price |
 tissue array) Blood vessel disease spectrum (blood vessel cancer progression) tissue array |
|
SO8010 |
TissueArray |
each |
EUR 306 |
|
Description: Blood vessel disease spectrum (blood vessel cancer progression) tissue array, 80 cases/80 cores |
 Foam Dewar - Mini Vessel - 130 ml |
|
M-FD-130 |
MiTeGen |
130 ML |
EUR 50 |
|
Description: Foam Dewar - Mini Vessel - 130 ml |
 HYPERSTACK VESSEL - 12 |
|
10012 |
Cusabio |
1/pk |
EUR 3470.4 |
|
Description: Stackable Cell Culture; High Yield Perf Cell Culture Chambers |
 HYPERSTACK VESSEL - 36 |
|
10036 |
CORNING |
1/pk |
EUR 3672 |
|
Description: Stackable Cell Culture; High Yield Perf Cell Culture Chambers |
 HYPERSTACK VESSEL - 12 LAYER, NT,S,1/4 |
|
10013 |
CORNING |
1/pk |
EUR 3631.2 |
|
Description: Stackable Cell Culture; High Yield Perf Cell Culture Chambers |
 HYPERSTACK VESSEL - 36 LAYER,NT,S,1/2 |
|
10037 |
CORNING |
1/pk |
EUR 3566.4 |
|
Description: Stackable Cell Culture; High Yield Perf Cell Culture Chambers |
 Blood Vessel: Artery Lysate |
|
21-270 |
ProSci |
0.1 mg |
EUR 468.6 |
|
Description: Monkey (Rhesus) blood vessel artery tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The monkey (Rhesus) blood vessel artery tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the blood vessel artery tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The blood vessel artery tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
 Total Protein - Lupus: Blood Vessel: Artery |
|
P1236013Lup |
Biochain |
1 mg |
EUR 471 |
 SINGLE-USE QUENCH BAG FOR HYPERSTACK® VESSEL, 5L |
|
91-200-76 |
CORNING |
1/pk |
EUR 223.2 |
|
Description: Flexible Containers; Bioprocess Bags and Parts |
 SINGLE-USE MEDIA BAG FOR HYPERSTACK® VESSEL, 20L |
|
91-200-77 |
CORNING |
1/pk |
EUR 206.4 |
|
Description: Flexible Containers; Bioprocess Bags and Parts |
 cDNA - Human Adult Normal Tissue: Blood Vessel: Vein |
|
C1234020-10 |
Biochain |
10 reactions |
EUR 215 |
 SINGLE-USE TRYPSIN BAG FOR HYPERSTACK® VESSEL, 5L |
|
91-200-75 |
CORNING |
1/pk |
EUR 218.4 |
|
Description: Flexible Containers; Bioprocess Bags and Parts |
These information assist ring opening of the furan by way of a reactive gamma-keto-alpha,beta-unsaturated aldehyde intermediate. Within the presence of UDP-glucuronic acid, prazosin underwent conjugation to type an N-glucuronide not reported beforehand. Our in vitro investigations have revealed further metabolic transformations of prazosin and have proven the potential of prazosin to endure bioactivation by means of metabolism of the furan ring to a reactive intermediate.
