Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in vitro.

Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in vitro. post thumbnail image

FR429, an ellagitannin (a sort of polyphenol), is remoted and purified from Polygonum capitatum Buch.-Ham.ex D. Don which is the unique natural drugs of the “Re-Lin-Qing” system used clinically to deal with urinary tract an infection in China. FR429 has been investigated for its antitumor potential in tumor-bearing nude mice in vivo, however its in vitro anti-tumor impact in hepatoma cell strains was low. Thus, it was of our curiosity to analyze its metabolism pathways for supporting its in vivo antitumor potential. The metabolic profiles of FR429 have been studied in vitro by liquid chromatography coupled to ion lure time-of-flight mass spectrometry. Whole eight metabolites have been recognized in rat and human liver microsomes, cytosol, and rat main hepatocytes in vitro.

Ellagic acid, a reported anti-angiogenic agent, was one of many most important metabolites in these organic matrices. Methylated metabolites catalyzed by catechol-O-methyl transferase (COMT) have been noticed primarily within the in vitro incubation with rat liver cytosol, which was verified by utilizing a COMT particular inhibitor entacapone and supported by molecular docking evaluation. Methylated and sulfated metabolites have been additionally present in rat main hepatocytes in a time-dependent method. In conclusion, the in vitro metabolism pathways of FR429 have been hydrolysis, methylation and sulfation. The anti-tumor results of its main metabolites must be additional studied.

The metabolism of the fragrant amine 1,3-diaminobenzene (MPD) was studied in vitro by use of the perfused rat liver, main rat hepatocyte cultures and hepatic rat microsomes. The metabolites shaped have been in contrast with urinary metabolites excreted by the rat in vivo. Metabolites of [(14)C]MPD excreted by the perfused liver have been discovered to be equivalent with urinary excreted metabolites in vivo, three of which have been discovered to correlate with the N-acetylated derivatives N,N’-diacetyl-1,3-diaminobenzene, N,N’-diacetyl-2,4-diaminophenol and N-acetyl-1,3-diaminobenzene.

Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in vitro.

Additionally, the first hepatocyte cultures shaped the metabolites discovered within the urine. Nonetheless, a number of different metabolites, together with some glucuronic acid conjugates, may very well be detected within the tradition medium. In distinction to the perfused liver and the first hepatocyte cultures, a reconstituted microsomal system was unable to type any of the metabolites shaped by the opposite in vitro fashions and in vivo.

Inhibition of NADPH-cytochrome P450 reductase by tannic acid in rat liver microsomes and first hepatocytes: methodological artifacts and utility to ischemia-reperfusion damage.

Tannic acid (TA) inhibits nicotinamide adenine dinucleotide phosphate (NADPH)-cytochrome P450 reductase (CPR) exercise, which is measured by discount of cytochrome c, in rat liver microsomes (RLMs). Within the present examine, we observed that TA immediately reduces cytochrome c within the absence of microsomes, thus confounding the CPR exercise assay. A way is offered that measures CPR exercise within the presence of TA by subtracting the cytochrome c discount within the absence of NADPH (TA impact) from that within the presence of NADPH (TA plus CPR impact).

The strategy was used to find out the inhibitory impact of TA in RLMs, recombinant CPR enzyme, and first hepatocytes. Moreover, utility of TA in a examine of position of CPR in a main rat hepatocyte mannequin of ischemia-reperfusion (IR) was investigated. TA confirmed concentration-dependent, full inhibition of CPR with half maximal inhibitory focus (IC(50) ) values of 58.2 μM in RLMs and 54.6 and 275 μM in main rat hepatocytes within the absence and presence of serum within the medium, respectively. Moreover, inhibition of CPR by TA was related to a major discount in reactive oxygen species and cell dying after IR damage. These information could also be helpful in future research utilizing TA as an inhibitor of CPR in microsomes and first hepatocytes.

Comparative metabolism of 1,2,3,3,3-pentafluoropropene in female and male mouse, rat, canine, and human liver microsomes and cytosol and male rat hepatocytes by way of oxidative dehalogenation and glutathione S-conjugation pathways.

In vitro metabolism of 1,2,3,3,3-pentafluoropropene (PFP) was investigated within the current examine. PFP was metabolized by way of cytochrome P450-catalyzed oxidative dehalogenation in liver microsomes and glutathione transferase (GST)-catalyzed conjugation in liver microsomes and cytosol. Two oxidation merchandise, 2,3,3,3-tetrafluoropropionaldehyde (TPA) and three,3,3-trifluoropyruvaldehyde (TFPA), and two GSH conjugates, S-(2,3,3,3-tetrafluoropropenyl)-GSH (TFPG) and S-(1,2,3,3,3-pentafluoropropyl)-GSH (PFPG) have been recognized. Enzyme kinetic parameters for the formation of TFPA, TFPG, and PFPG have been obtained in female and male rat, mouse, canine, and human liver microsomes and cytosol and have been confirmed utilizing freshly remoted male rat hepatocytes.

For the TFPA pathway, canine microsomes exhibited a lot bigger Okay(m) values than rat, mouse, and human microsomes. Intercourse variations within the charges of metabolism inside a given species have been minor and usually have been lower than 2-fold. Throughout the species, liver microsomes have been the first subcellular fraction for GSH S-conjugation and the obvious response charges for the formation of TFPG have been a lot better than these for PFPG in liver microsomes. PFPG was unstable and had a half-life of roughly 3.9 h in a phosphate buffer (pH 7.Four and 37°C).

Rat Liver Tissue Lysate

LYSATE0003 200ug
EUR 150
Description: This cell lysate is prepared from rat liver tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Rat Ferritin (Liver) Antibody

11901-05011 150 ug
EUR 217

Rat Liver PrimaCell: Hepatocytes

2-82595 1 Kit Ask for price

cDNA from Liver Cirrhosis: Liver

C1236149Lcs 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Liver Membrane Liver Cirrhosis Lysate

XBL-10671 0.1 mg
EUR 626.75
Description: Human liver tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human liver tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated liver tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated liver tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Rat Phosphofructokinase, Liver (PFKL) Protein

20-abx167625
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Liver Whole tissue lysate

RAL-1464 1 mg
EUR 524

Rat Liver glycogen ELISA kit

E02H0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Liver glycogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Liver glycogen ELISA kit

E02H0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Liver glycogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Liver glycogen ELISA kit

E02H0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Liver glycogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Total Protein from Liver Cirrhosis: Liver

P1236149Lcs 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Liver Cirrhosis: Liver

P3236149Lcs 0.1 mg
EUR 408
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA from Liver Cirrhosis: Liver

R1236149Lcs-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Paraffin Tissue Section - Liver Cirrhosis: Liver

T2236149Lcs 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Liver Lysate

1304 0.1 mg
EUR 191
Description: Liver tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Liver Lysate

1404 0.1 mg
EUR 191
Description: Liver tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Liver Lysate

1464 0.1 mg
EUR 191
Description: Liver tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Liver Lysate

21-105 0.1 mg
EUR 285.5
Description: Bovine liver tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The bovine liver tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the liver tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The liver tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Liver Lysate

21-302 0.1 mg
EUR 285.5
Description: Monkey (Rhesus) liver tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The monkey (Rhesus) liver tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the liver tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The liver tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Liver Lysate

21-406 0.1 mg
EUR 285.5
Description: Porcine liver tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The porcine liver tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the liver tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The liver tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Liver Lysate

21-419 0.1 mg
EUR 285.5
Description: Rabbit liver tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The rabbit liver tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the liver tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The liver tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Liver Dissociation System 4 (Hepatocytes, rat), Rat

4-20304 ea Ask for price

Phosphofructokinase, Liver (PFKL) Polyclonal Antibody (Rat)

4-PAD406Ra01
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Phosphofructokinase, Liver (PFKL)

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

SED406Ra-10x96wellstestplate 10x96-wells test plate
EUR 5124.2
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Phosphofructokinase, Liver (PFKL) in tissue homogenates, cell lysates and other biological fluids.

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

SED406Ra-1x48wellstestplate 1x48-wells test plate
EUR 509.64
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Phosphofructokinase, Liver (PFKL) in tissue homogenates, cell lysates and other biological fluids.

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

SED406Ra-1x96wellstestplate 1x96-wells test plate
EUR 685.2
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Phosphofructokinase, Liver (PFKL) in tissue homogenates, cell lysates and other biological fluids.

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

SED406Ra-5x96wellstestplate 5x96-wells test plate
EUR 2783.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Phosphofructokinase, Liver (PFKL) in tissue homogenates, cell lysates and other biological fluids.

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

4-SED406Ra
  • EUR 5175.00
  • EUR 2734.00
  • EUR 686.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Phosphofructokinase, Liver (PFKL) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Phosphofructokinase, Liver ELISA Kit (PFKL)

RK03883 96 Tests
EUR 521

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

RD-PFKL-Ra-48Tests 48 Tests
EUR 557

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

RD-PFKL-Ra-96Tests 96 Tests
EUR 775

Rat Ferritin (Liver) Antibody (Biotin Conjugate)

11901-05021 150 ug
EUR 276

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

DLR-PFKL-Ra-48T 48T
EUR 549
Description: A sandwich quantitative ELISA assay kit for detection of Rat Phosphofructokinase, Liver (PFKL) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

DLR-PFKL-Ra-96T 96T
EUR 718
Description: A sandwich quantitative ELISA assay kit for detection of Rat Phosphofructokinase, Liver (PFKL) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

abx573958-96tests 96 tests
EUR 739

Rat Phosphofructokinase, Liver (PFKL) CLIA Kit

20-abx494255
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Glycogen Phosphorylase, Liver (PYGL) Protein

20-abx066870
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Glycogen Phosphorylase, Liver (PYGL) Protein

20-abx066872
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Glycogen Phosphorylase, Liver (PYGL) Protein

20-abx066873
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat FibrOut 2, for cartilage, liver

4-20529 1 ml Ask for price

Rat FibrOut 2, for cartilage, liver

4-20530 5 x 1 ml Ask for price

Rat Liver OptiTDS: Tissue Dissociation System

4-28322 1 Kit Ask for price

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

20-abx155968
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

RDR-PFKL-Ra-48Tests 48 Tests
EUR 583

Rat Phosphofructokinase, Liver (PFKL) ELISA Kit

RDR-PFKL-Ra-96Tests 96 Tests
EUR 811

Rat liver ferritin purified, ELISA grade

FERT21-R-50 50 ug
EUR 408

Rabbit Anti-Rat liver Ferritin IgG

FERT25-A 100 ul
EUR 482

Chicken anti-Rat liver Ferritin IgG

FERT26-A 100 ul
EUR 482

Rat Collectin Liver 1 ELISA kit

E02C0405-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Collectin Liver 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Collectin Liver 1 ELISA kit

E02C0405-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Collectin Liver 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Collectin Liver 1 ELISA kit

E02C0405-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Collectin Liver 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Glycogen Phosphorylase, Liver ELISA kit

E02P0171-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Glycogen Phosphorylase, Liver in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Glycogen Phosphorylase, Liver ELISA kit

E02P0171-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Glycogen Phosphorylase, Liver in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Glycogen Phosphorylase, Liver ELISA kit

E02P0171-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Glycogen Phosphorylase, Liver in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Liver specific lipootein ELISA kit

E02L0280-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rat Liver specific lipootein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Liver specific lipootein ELISA kit

E02L0280-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rat Liver specific lipootein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Liver specific lipootein ELISA kit

E02L0280-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rat Liver specific lipootein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

cDNA from Rat Normal Tissue: Liver

C1434149 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Rat Amphoterin-induced protein 3 (Amigo3)

1-CSB-MP802260RA
  • EUR 293.00
  • EUR 963.00
  • EUR 409.00
  • EUR 717.00
  • 100ug
  • 1MG
  • 200ug
  • 500ug
Description: Recombinant Rat Amphoterin-induced protein 3(Amigo3) expressed in Mammalian cell

Rat Prolactin Induced Protein (PIP) Protein

20-abx068687
  • EUR 718.00
  • EUR 286.00
  • EUR 2221.00
  • EUR 857.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Prolactin Induced Protein (PIP) Protein

20-abx165970
  • EUR 704.00
  • EUR 286.00
  • EUR 2193.00
  • EUR 843.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Liver Cancer Exosome

P141-LV - Ask for price

Liver Arginase Antibody

49867-100ul 100ul
EUR 333

Liver Arginase Antibody

49867-50ul 50ul
EUR 239

Chang Liver (HeLa)

C0050007 One Frozen vial
EUR 543

CK LIVER 1kg*

43023-2 1 kg
EUR 240.09

Human Liver Ferritin

7-05176 200µg Ask for price

Human Liver Ferritin

7-05177 1mg Ask for price

Human Liver Ferritin

7-05178 10mg Ask for price

Liver Ferritin Protein

20-abx260074
  • EUR 2903.00
  • EUR 648.00
  • EUR 286.00
  • 10 mg
  • 1 mg
  • 200 ug

liver Arginase Antibody

abx234800-100ug 100 ug
EUR 481

liver Arginase Antibody

abx234801-100ug 100 ug
EUR 481

anti-liver Arginase

YF-PA10306 50 ug
EUR 363
Description: Mouse polyclonal to liver Arginase

anti-liver Arginase

YF-PA10307 50 ug
EUR 363
Description: Mouse polyclonal to liver Arginase

anti-liver Arginase

YF-PA10308 100 ul
EUR 403
Description: Rabbit polyclonal to liver Arginase

anti-liver Arginase

YF-PA10309 100 ug
EUR 403
Description: Rabbit polyclonal to liver Arginase

anti-liver FABP

YF-PA11679 50 ul
EUR 363
Description: Mouse polyclonal to liver FABP

anti-liver FABP

YF-PA11680 100 ug
EUR 403
Description: Rabbit polyclonal to liver FABP

anti-liver FABP

YF-PA11681 100 ug
EUR 403
Description: Rabbit polyclonal to liver FABP

anti-liver FABP

YF-PA23687 50 ul
EUR 334
Description: Mouse polyclonal to liver FABP

Ferritin, Human liver

P1449-100
EUR 164

Ferritin protein (Liver)

30-AF10 1 mg
EUR 308
Description: Highly purfied Ferritin protein isolated from human liver

Liver Tumor Lysate

1330 0.1 mg
EUR 254
Description: Liver tumor tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Liver Lupus Lysate

XBL-10359 0.1 mg
EUR 663.5
Description: Human liver tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human liver tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the liver tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The liver tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Fetal Liver Lysate

XBL-10409 0.1 mg
EUR 285.5
Description: Fetal human liver tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The fetal human liver tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the liver tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The liver tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Liver Cytoplasmic Lysate

XBL-10666 0.1 mg
EUR 227.75
Description: Human liver tissue cytoplasmic protein lysate was prepared by isolating the cytoplasmic protein from whole tissue homogenates using a proprietary technique. The human liver tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The cytoplasmic protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, glycerol, and a cocktail of protease inhibitors. For quality control purposes, the isolated liver tissue cytoplasmic protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated liver tissue cytoplasmic protein is then Western analyzed by GAPDH antibody, and the expression level is consistent with each lot.

Liver Membrane Lysate

XBL-10667 0.1 mg
EUR 516.5
Description: Human liver tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human liver tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated liver tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated liver tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Phosphofructokinase, Liver (PFKL) Polyclonal Antibody (Rat), APC

4-PAD406Ra01-APC
  • EUR 364.00
  • EUR 3545.00
  • EUR 980.00
  • EUR 467.00
  • EUR 227.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Phosphofructokinase, Liver (PFKL). This antibody is labeled with APC.

Phosphofructokinase, Liver (PFKL) Polyclonal Antibody (Rat), Biotinylated

4-PAD406Ra01-Biotin
  • EUR 325.00
  • EUR 2658.00
  • EUR 777.00
  • EUR 400.00
  • EUR 225.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Phosphofructokinase, Liver (PFKL). This antibody is labeled with Biotin.

Phosphofructokinase, Liver (PFKL) Polyclonal Antibody (Rat), Cy3

4-PAD406Ra01-Cy3
  • EUR 444.00
  • EUR 4685.00
  • EUR 1265.00
  • EUR 581.00
  • EUR 261.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Phosphofructokinase, Liver (PFKL). This antibody is labeled with Cy3.

Phosphofructokinase, Liver (PFKL) Polyclonal Antibody (Rat), FITC

4-PAD406Ra01-FITC
  • EUR 311.00
  • EUR 2856.00
  • EUR 804.00
  • EUR 393.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Phosphofructokinase, Liver (PFKL). This antibody is labeled with FITC.

Phosphofructokinase, Liver (PFKL) Polyclonal Antibody (Rat), HRP

4-PAD406Ra01-HRP
  • EUR 332.00
  • EUR 3089.00
  • EUR 866.00
  • EUR 421.00
  • EUR 213.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Phosphofructokinase, Liver (PFKL). This antibody is labeled with HRP.

The intrinsic clearance values for the formation of TFPA have been a lot better than these for the formation of GSH S-conjugates, suggesting that cytochrome P450-mediated oxidation is the first pathway for the metabolism of PFP at comparatively low PFP concentrations. As a result of saturation of the GST-mediated reactions was not reached on the highest potential PFP focus, GSH S-conjugation might develop into a way more necessary pathway at increased PFP concentrations (relative to the Okay(m) for TFPA).

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