extract – Page 2 – Asociación Española de Toxicología (AETOX) ISSN: 1697-0748

Microarray analysis of differentially expressed long non-coding RNAs in daidzein-treated lung cancer cellsMicroarray analysis of differentially expressed long non-coding RNAs in daidzein-treated lung cancer cells

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Daidzein has been discovered to considerably inhibit the proliferation of lung most cancers cells, whereas its potential molecular mechanisms stay unclear. To find out the molecular mechanism of daidzein on

Effects of sclerostin antibody on bone healingEffects of sclerostin antibody on bone healing

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Selling bone therapeutic after a fracture has been a frequent topic of analysis. Not too long ago, sclerostin antibody (Scl-Ab) has been launched as a brand new anabolic agent for the remedy

Leptin modulates gene expression in the heart, cardiomyocytes and the adipose tissue thus mitigating LPS-induced damageLeptin modulates gene expression in the heart, cardiomyocytes and the adipose tissue thus mitigating LPS-induced damage

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Leptin is an adipokine of pleiotropic results linked to power metabolism, satiety, the immune response, and cardioprotection. Now we have lately proven that leptin causally conferred resistance to myocardial infarction-induced

Hedgehog signaling in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironmentHedgehog signaling in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment

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The Hedgehog (HH) signaling pathway performs necessary roles in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH signaling activation could speed up the expansion of gastrointestinal tumors and result in tumor

Anti-laminin 332 antibody detection using biochip immunofluorescence microscopy in a real-life cohort of Italian patients with mucous membrane pemphigoidAnti-laminin 332 antibody detection using biochip immunofluorescence microscopy in a real-life cohort of Italian patients with mucous membrane pemphigoid

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Mucous membrane pemphigoid (MMP) with anti-laminin 332 autoantibodies could also be related to malignancies, nevertheless, present serological assays have appreciable limitations. At current, no business take a look at for

VCAM1-α4β1 integrin interaction mediates interstitial tissue reconstruction in 3-D re-aggregate culture of dissociated prepubertal mouse testicular cellsVCAM1-α4β1 integrin interaction mediates interstitial tissue reconstruction in 3-D re-aggregate culture of dissociated prepubertal mouse testicular cells

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Roles of interstitial tissue in morphogenesis of testicular constructions stay much less nicely understood. To research the roles of CD34+ cells within the reconstruction of interstitial tissue containing Leydig cells (LCs),

Klotho induces insulin resistance possibly through interference with GLUT4 translocation and activation of Akt, GSK3β, and PFKfβ3 in 3T3-L1 adipocyte cells.Klotho induces insulin resistance possibly through interference with GLUT4 translocation and activation of Akt, GSK3β, and PFKfβ3 in 3T3-L1 adipocyte cells.

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Klotho is taken into account as an anti-aging issue inducing insulin resistance and concerned in kind 2 diabetes. Nevertheless, mechanisms by which klotho induces insulin resistance stay to be understood.

Affiblot: a dot blot-based screening device for selection of reliable antibodiesAffiblot: a dot blot-based screening device for selection of reliable antibodies

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The important thing issue within the improvement of antibody-based assays is to search out an antibody that has an applicable affinity, excessive specificity, and low cross-reactivity. Nonetheless, this process is just not straightforward

False-Negative Platelet Factor 4 Antibodies and Serotonin Release Assay and the Utility of Repeat Testing in the Diagnosis of Heparin-Induced Thrombocytopenia and Thrombosis.False-Negative Platelet Factor 4 Antibodies and Serotonin Release Assay and the Utility of Repeat Testing in the Diagnosis of Heparin-Induced Thrombocytopenia and Thrombosis.

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To report a case of false-negative serological checks within the prognosis of heparin-induced thrombocytopenia (HIT) adopted by a short evaluation of the literature on this matter.A 75-year-old Caucasian feminine affected

Molecular Mechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants.Molecular Mechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants.

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Krabbe illness is a extreme, deadly neurodegenerative dysfunction brought on by defects within the lysosomal enzyme galactocerebrosidase (GALC). The right concentrating on of GALC to the lysosome is important for the degradation