Defining Proximity Proteomics of Histone Modifications by Antibody-mediated Protein A-APEX2 LabelingDefining Proximity Proteomics of Histone Modifications by Antibody-mediated Protein A-APEX2 Labeling
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Proximity labeling catalyzed by promiscuous enzymes, reminiscent of APEX2, has emerged as a robust strategy to characterize multiprotein complexes and protein-protein interactions. Nonetheless, present strategies rely upon the expression of
