Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology.Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology.
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Though prediction of clearance utilizing hepatocytes and liver microsomes has lengthy performed a decisive position in drug discovery, it’s extensively acknowledged that reliably correct prediction just isn’t but achievable regardless
